Global Stability of Within-Host Virus Dynamics Models with Multitarget Cells

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Global Properties of Virus Dynamics Models with Multitarget Cells and Discrete-Time Delays

We propose a class of virus dynamics models with multitarget cells and multiple intracellular delays and study their global properties. The first model is a 5-dimensional system of nonlinear delay differential equations DDEs that describes the interaction of the virus with two classes of target cells. The second model is a 2n 1 -dimensional system of nonlinear DDEs that describes the dynamics o...

متن کامل

Global Asymptotic Stability of Equilibria in Models for Virus Dynamics

In this paper several models in virus dynamics with and without immune response are discussed concerning asymptotic behaviour. The case of immobile cells but diffusing viruses and T-cells is included. It is shown that, depending on the value of the basic reproductive number R0 of the virus, the corresponding equilibrium is globally asymptotically stable. If R0 < 1 then the virus-free equilibriu...

متن کامل

Stability analysis of within-host parasite models with delays.

We provide a global analysis of systems of within-host parasitic infections. The systems studied have parallel classes of different length of latently infected target cells. These systems can also be thought as systems arising from within-host parasitic systems with distributed continuous delays. We compute the basic reproduction ratio R0 for the systems under consideration. If R0< or =1 the pa...

متن کامل

Within-host virus models with periodic antiviral therapy.

This paper investigates the effect of drug treatment on the standard within-host virus model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimens, and we quantitatively characterize successful drugs or drug combinations, both theoretically and numerically. We also consider certain optimization problems, motivated for instance, by the...

متن کامل

Within-host virus models with periodic antiviral therapy

This paper investigates the effect of drug treatment on the standard within-host virus model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimens, and we quantitatively characterize successful drugs or drug combinations, both theoretically and numerically. We also consider certain optimization problems, motivated for instance, by the...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Mathematics

سال: 2018

ISSN: 2227-7390

DOI: 10.3390/math6070118